JNJ

234.53

+0.17%↑

UNH

279.4

-2.23%↓

TMO

571.51

-2.42%↓

ABT

107.78

-0.01%↓

ISRG

468.22

-5.55%↓

JNJ

234.53

+0.17%↑

UNH

279.4

-2.23%↓

TMO

571.51

-2.42%↓

ABT

107.78

-0.01%↓

ISRG

468.22

-5.55%↓

JNJ

234.53

+0.17%↑

UNH

279.4

-2.23%↓

TMO

571.51

-2.42%↓

ABT

107.78

-0.01%↓

ISRG

468.22

-5.55%↓

JNJ

234.53

+0.17%↑

UNH

279.4

-2.23%↓

TMO

571.51

-2.42%↓

ABT

107.78

-0.01%↓

ISRG

468.22

-5.55%↓

JNJ

234.53

+0.17%↑

UNH

279.4

-2.23%↓

TMO

571.51

-2.42%↓

ABT

107.78

-0.01%↓

ISRG

468.22

-5.55%↓

Search

Denali Therapeutics Inc

Open

SectorHealthcare

21.23 -8.73

Overview

Share price change

24h

Current

Min

21.03

Max

22.65

Key metrics

By Trading Economics

Income

-2.8M

-127M

Employees

517

EBITDA

-12M

-134M

Recommendations

By TipRanks

Recommendations

Strong Buy

12 Months Forecast

+45.12% upside

Dividends

By Dow Jones

Next Earnings

25 Feb 2026

Market Stats

By TradingEconomics

Market Cap

973M

3.2B

Previous open

29.96

Previous close

21.23

News Sentiment

By Acuity

63%

37%

305 / 352 Healthcare

Technical Score

By Trading Central

Confidence

Strong Bearish Evidence

Denali Therapeutics Inc Chart

Past performance is not a reliable indicator of future results.

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Peer Comparison

Price change

Denali Therapeutics Inc Forecast

Price Target

By TipRanks

45.12% upside

12 Months Forecast

Average 33 USD  45.12%

High 40 USD

Low 25 USD

Based on 12 Wall Street analysts offering 12 month price targets forDenali Therapeutics Inc - Dist in the last 3 months.

Rating Consensus

By TipRanks

Strong Buy

12 ratings

12

Buy

0

Hold

0

Sell

Technical Score

By Trading Central

13.355 / 16.44Support & Resistance

Short Term

Strong Bearish Evidence

Intermediate Term

Neutral Evidence

Long Term

Strong Bearish Evidence

Sentiment

By Acuity

305 / 352 Healthcare

News Sentiment

Bearish Evidence

Volatility

Below average

News Volume (RCV)

Above average

Financials

Selling and administration expenses

Operating expenses

Pre-tax profit

Sales

Cost of sales

Gross profit on sales

Interest expense on debt

EBITDA

Operating profit

$

About Denali Therapeutics Inc

Denali Therapeutics Inc., a biopharmaceutical company, develops a portfolio of product candidates engineered to cross the blood-brain barrier for neurodegenerative diseases and lysosomal storage diseases in the United States. The company's transport vehicle (TV)-enabled programs include DNL310 ETV, an IDS enzyme replacement therapy program for MPS II; TAK-594/DNL593 which is in Phase 1/II for frontotemporal dementia-granulin; DNL126 program for MPS IIIA; and DNL622 for MPS I, as well as other preclinical programs that target amyloid beta and HER2. Its brain-penetrant small molecule programs comprise BIIB122/DNL151 LRRK2 inhibitor program for Parkinson's disease; SAR443820/DNL788 RIPK1 inhibitor program for CNS disease; DNL343 eIF2B Activator program for amyotrophic lateral sclerosis; and SAR443122/DNL758 RIPK1 inhibitor program for peripheral inflammatory diseases. It also provides early stage program include TAK-594/DNL593 program for FTD-GRN; DNL126 program for MPS IIIA, a Sanfilippo Syndrome A; DNL622 for MPS I which is Hurler syndrome; Antibody Transport Vehicle Amyloid beta program; Oligonucleotide Transport Vehicle platform, a novel class of biotherapeutics to address the root cause of diseases through modulation of gene expression; and other TV-enabled discovery programs. The company has collaboration agreements with Biogen MA Inc. and Biogen International GmbH; Genzyme Corporation; Takeda Pharmaceutical Company Limited; F-star Gamma Limited, F-star Biotechnologische Forschungs-und Entwicklungsges m.b.H, and F-star Biotechnology Limited; and Genentech, Inc. The company was formerly known as SPR Pharma Inc. and changed its name to Denali Therapeutics Inc. in March 2015. Denali Therapeutics Inc. was incorporated in 2013 and is headquartered in South San Francisco, California.
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