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Denali Therapeutics Inc

Closed

SectorHealthcare

22.51 -1.79

Overview

Share price change

24h

Current

Min

21.92

Max

23.03

Key metrics

By Trading Economics

Income

102K

-128M

EPS

-0.69

Employees

507

EBITDA

-937K

-126M

Recommendations

By TipRanks

Recommendations

Strong Buy

12 Months Forecast

+48.57% upside

Dividends

By Acuity

Next Earnings

7 Aug 2026

Market Stats

By TradingEconomics

Market Cap

1.2B

4.2B

Previous open

24.3

Previous close

22.51

News Sentiment

By Acuity

50%

50%

153 / 342 Healthcare

Denali Therapeutics Inc Chart

Past performance is not a reliable indicator of future results.

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Peer Comparison

Price change

Denali Therapeutics Inc Forecast

Price Target

By TipRanks

48.57% upside

12 Months Forecast

Average 34.2 USD  48.57%

High 42 USD

Low 25 USD

Based on 12 Wall Street analysts offering 12 month price targets forDenali Therapeutics Inc - Dist in the last 3 months.

Rating Consensus

By TipRanks

Strong Buy

12 ratings

12

Buy

0

Hold

0

Sell

Sentiment

By Acuity

153 / 342 Healthcare

News Sentiment

Neutral

Volatility

Below average

News Volume (RCV)

Below average

Financials

Selling and administration expenses

Operating expenses

Pre-tax profit

Sales

Cost of sales

Gross profit on sales

Interest expense on debt

EBITDA

Operating profit

$

About Denali Therapeutics Inc

Denali Therapeutics Inc., a biopharmaceutical company, develops a portfolio of product candidates engineered to cross the blood-brain barrier for neurodegenerative diseases and lysosomal storage diseases in the United States. The company's transport vehicle (TV)-enabled programs include DNL310 ETV, an IDS enzyme replacement therapy program for MPS II; TAK-594/DNL593 which is in Phase 1/II for frontotemporal dementia-granulin; DNL126 program for MPS IIIA; and DNL622 for MPS I, as well as other preclinical programs that target amyloid beta and HER2. Its brain-penetrant small molecule programs comprise BIIB122/DNL151 LRRK2 inhibitor program for Parkinson's disease; SAR443820/DNL788 RIPK1 inhibitor program for CNS disease; DNL343 eIF2B Activator program for amyotrophic lateral sclerosis; and SAR443122/DNL758 RIPK1 inhibitor program for peripheral inflammatory diseases. It also provides early stage program include TAK-594/DNL593 program for FTD-GRN; DNL126 program for MPS IIIA, a Sanfilippo Syndrome A; DNL622 for MPS I which is Hurler syndrome; Antibody Transport Vehicle Amyloid beta program; Oligonucleotide Transport Vehicle platform, a novel class of biotherapeutics to address the root cause of diseases through modulation of gene expression; and other TV-enabled discovery programs. The company has collaboration agreements with Biogen MA Inc. and Biogen International GmbH; Genzyme Corporation; Takeda Pharmaceutical Company Limited; F-star Gamma Limited, F-star Biotechnologische Forschungs-und Entwicklungsges m.b.H, and F-star Biotechnology Limited; and Genentech, Inc. The company was formerly known as SPR Pharma Inc. and changed its name to Denali Therapeutics Inc. in March 2015. Denali Therapeutics Inc. was incorporated in 2013 and is headquartered in South San Francisco, California.
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