Search

Ionis Pharmaceuticals Inc

Closed

SectorHealthcare

44.93 -4.49

Overview

Share price change

24h

Current

Min

44.61

Max

47.31

Key metrics

By Trading Economics

Income

-22M

-115M

Sales

22M

268M

EPS

-0.7

Profit margin

-42.787

Employees

1,480

EBITDA

-37M

-105M

Recommendations

By TipRanks

Recommendations

Strong Buy

12 Months Forecast

+87.95% upside

Dividends

By Acuity

Next Earnings

28 paź 2026

Market Stats

By TradingEconomics

Market Cap

-700M

8.5B

Previous open

49.42

Previous close

44.93

News Sentiment

By Acuity

61%

39%

277 / 339 Ranking in Healthcare

Ionis Pharmaceuticals Inc Chart

Wyniki osiągnięte w przeszłości nie są gwarantem przyszłych wyników.

Related News

16 wrz 2026, 20:08 UTC

Social Media
Macro Event

Ionis Pharmaceuticals shares fell amid challenges from its failed Phase 3 ATTR partnership, erasing about $4.63 billion in market value.

15 wrz 2026, 23:01 UTC

Ionis Pharmaceuticals shares are trading higher in after-market hours, despite a broader market decline indicated by a sharp drop in the Empire State Manufacturing Index.

14 wrz 2026, 23:16 UTC

Ionis Pharmaceuticals Inc. shares are higher in after-market trading, though still below the 20-day moving average after six consecutive sessions of declines.

11 wrz 2026, 23:56 UTC

News

Ionis Pharmaceuticals received FDA approval for ZANVASTRO. Shares are higher in after-market trading, reflecting positive sentiment despite a setback in a partnered trial.

10 wrz 2026, 19:16 UTC

News

Ionis Pharmaceuticals shares are lower as HC Wainwright cuts the price target from $115.00 to $100.00 while maintaining a "buy" rating.

9 wrz 2026, 22:51 UTC

Ionis Pharmaceuticals shares are lower in after-market hours. Broader market trends reflect concerns over rising crude oil prices exceeding $100 amid Middle East tensions.

8 wrz 2026, 23:41 UTC

Ionis Pharmaceuticals Inc shares are lower in after-market trading, reversing earlier gains and reflecting overall weakness without any specific news to explain the decline.

5 wrz 2026, 00:05 UTC

News

Ionis Pharmaceuticals shares are lower in after-market hours following Novartis' announcement that the pelacarsen Phase 3 study did not meet its primary endpoint.

4 wrz 2026, 23:02 UTC

News

Ionis Pharmaceuticals shares declined in after-market trading following Novartis' announcement of the failed pelacarsen Phase 3 study to reduce cardiovascular events.

3 wrz 2026, 22:02 UTC

News

Ionis Pharmaceuticals shares are higher in after-hours trading following FDA approval for Zanvastro, the first treatment for Alexander disease.

2 wrz 2026, 23:01 UTC

Ionis Pharmaceuticals Inc shares are lower in after-market hours, reflecting notable selling pressure since Wednesday's close. No specific news was identified to explain the decline.

1 wrz 2026, 22:01 UTC

Ionis Pharmaceuticals Inc shares are trading higher in after-market hours, reversing a trend of five consecutive lower sessions. No specific news was identified.

31 sie 2026, 19:56 UTC

News

Ionis Pharmaceuticals shares are lower today following negative results from a failed trial of Wainua, which did not meet its primary endpoint.

28 sie 2026, 21:01 UTC

Ionis Pharmaceuticals Inc. shares are lower in after-market trading, continuing a trend of four consecutive daily declines despite remaining above the 20-day moving average.

27 sie 2026, 23:46 UTC

Ionis Pharmaceuticals shares traded near unchanged during after-market hours, reflecting routine activity. The stock has declined for three consecutive sessions.

26 sie 2026, 23:51 UTC

Ionis Pharmaceuticals is rising in after-market hours, reflecting broader market gains amid positive economic data on durable goods orders and inflation indicators.

25 sie 2026, 23:01 UTC

Ionis Pharmaceuticals Inc shares are higher in after-market hours, maintaining momentum above the 20-day moving average amid a broader market reaction to falling crude oil prices.

24 sie 2026, 23:11 UTC

Ionis Pharmaceuticals shares are higher in after-market hours following a session low. Broader market performance remains subdued amid ongoing geopolitical concerns.

22 sie 2026, 00:01 UTC

Ionis Pharmaceuticals Inc is higher in after-market trading, reflecting strength amid a broader market rebound. The stock remains above its 20-day moving average.

21 sie 2026, 22:51 UTC

Ionis Pharmaceuticals Inc shares are trading higher during after-market hours, remaining above the 20-day moving average and near the upper end of their one-month range.

20 sie 2026, 20:02 UTC

News
Event

Ionis Pharmaceuticals will present new data on hypertriglyceridemia treatments at the European Society of Cardiology Congress, though shares are trading lower today.

19 sie 2026, 23:06 UTC

News

Ionis Pharmaceuticals is advancing RG-6299 into a pivotal Phase III trial for IgA nephropathy in collaboration with Roche and Chugai. Shares are higher in after-market trading.

18 sie 2026, 20:06 UTC

Ionis Pharmaceuticals Inc shares are higher, supported by strong momentum above the 20-day moving average. No specific news was identified for today's move.

17 sie 2026, 23:01 UTC

Ionis Pharmaceuticals Inc shares are lower in after-market hours, reflecting a decline since Monday's close amid broader market weakness and geopolitical tensions.

14 sie 2026, 22:02 UTC

Ionis Pharmaceuticals shares are higher in after-market trading. No specific news was identified to explain the movement amid broader economic concerns.

13 sie 2026, 19:56 UTC

Ionis Pharmaceuticals Inc shares are lower today, reflecting broader market trends. First-time unemployment claims rose, but overall investor sentiment remains stable.

12 sie 2026, 23:56 UTC

Ionis Pharmaceuticals Inc. shares are lower in after-market trading, despite remaining above their 20-day moving average and within the upper range for the month.

11 sie 2026, 23:46 UTC

Ionis Pharmaceuticals shares are higher in after-market trading, reaching a high near the upper end of their one-month range. No specific news was identified.

10 sie 2026, 21:01 UTC

Ionis Pharmaceuticals Inc shares are lower in after-market hours. Broader market sentiment is cautious following weaker-than-expected labor market data.

7 sie 2026, 20:03 UTC

News

Ionis Pharmaceuticals shares are higher today amid increased market volume. HC Wainwright revised Q3 2026 loss estimates, maintaining a "Buy" rating.

Peer Comparison

Price change

Ionis Pharmaceuticals Inc Forecast

Price Target

By TipRanks

87.95% upside

12 Months Forecast

Average 84.278 USD  87.95%

High 104 USD

Low 54 USD

Based on 20 Wall Street analysts offering 12 month price targets forIonis Pharmaceuticals Inc - Dist in the last 3 months.

Rating Consensus

By TipRanks

Strong Buy

20 ratings

16

Buy

4

Hold

0

Sell

Sentiment

By Acuity

277 / 339 Ranking in Healthcare

News Sentiment

Bearish Evidence

Volatility

Below average

News Volume (RCV)

Below average

Financials

Selling and administration expenses

Operating expenses

Pre-tax profit

Sales

Cost of sales

Gross profit on sales

Interest expense on debt

EBITDA

Operating profit

$

About Ionis Pharmaceuticals Inc

Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapeutics in the United States. The company offers SPINRAZA for spinal muscular atrophy (SMA) in pediatric and adult patients; TEGSEDI, an antisense injection for the treatment of polyneuropathy caused by hereditary transthyretin amyloidosis in adults; and WAYLIVRA, an antisense medicine for treatment for familial chylomicronemia syndrome (FCS) and familial partial lipodystrophy. It also develops medicines for various indications that are in phase 3 study, including Eplontersen as a monthly self-administered subcutaneous injection to treat all types of ATTR; Olezarsen for patients with FCS and severe hypertriglyceridemia (SHTG); Donidalorsen for patients with hereditary angioedema; ION363 for patients with amyotrophic lateral sclerosis; Tofersen to inhibit the production of superoxide dismutase 1; Pelacarsen for patients with established cardiovascular disease and elevated lipoprotein(a); and Bepirovirsen to inhibit the production of viral proteins associated with hepatitis B virus. In addition, the company develops IONIS-FB-LRx to inhibit the production of complement factor B and the alternative complement pathway; and ION224 to reduce the production of diacylglycerol acyltransferase 2. It has a strategic collaboration with Biogen for the treatment of neurological disorders; and collaboration and license agreement with Metagenomi, Inc, AstraZeneca, Bayer AG, GlaxoSmithKline plc, Novartis, Roche, Swedish Orphan Biovitrum AB, and PTC Therapeutics. The company was incorporated in 1989 and is based in Carlsbad, California.
help-icon Live chat